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Original illustration for Sermorelin research notes: abstract molecular artwork in orange and teal
Original illustration by USA Peptide Vendors; artistic, not a structural model.

Growth & signaling research peptides

Sermorelin: from sequence to supplier

GHRH(1-29)-NH2, the shortest fully active fragment of growth hormone–releasing hormone. Sermorelin was used clinically to test and treat growth hormone deficiency in children before recombinant GH became standard.

GrowthCAS 86168-78-729 residuesGRF 1-29GHRH (1-29)-NH2Updated 2026-11-09

  1. Confirm what Sermorelin is

    Amino acid sequence · 29 residues
    1. Y1
    2. A2
    3. D3
    4. A4
    5. I5
    6. F6
    7. T7
    8. N8
    9. S9
    10. Y10
    11. R11
    12. K12
    13. V13
    14. L14
    15. G15
    16. Q16
    17. L17
    18. S18
    19. A19
    20. R20
    21. K21
    22. L22
    23. L23
    24. Q24
    25. D25
    26. I26
    27. M27
    28. S28
    29. R29
    CAS number
    86168-78-7
    Molecular formula
    C149H246N44O42S
    Molecular weight
    3357.9 g/mol
    PubChem CID
    16132413
    Length
    29 residues

    Verified 2026-11-09 against PubChem CID 16132413. Values we couldn't verify are left out.

  2. Know the proposed mechanism

    Sermorelin was used clinically to test and treat growth hormone deficiency in children before recombinant GH became standard.

    Mechanism map

    Evidence level: Clinical: pediatric diagnostic and treatment use (review). All mechanism maps

    Sermorelin mechanism diagramGHRH receptor agonism and pituitary growth hormone release. Targets: GHRH receptor. Response: GH release ↑. Uses reported: GH stimulation test, Growth in GH-deficient children.Sermorelin mechanism mapGHRH receptor agonism and pituitary growth hormone releaseSermorelinGHRH(1-29)-NH2GHRH receptoranterior pituitary [1]GH release ↑[1]GH stimulation test[1]Growth in GH-deficient children[1]Evidence: Clinical: pediatric diagnostic and treatment use (review). Numbers in bracketsrefer to the cited sources.usapeptidevendors.com · Research Use OnlyRECEPTORRESPONSEUSES REPORTED
    Clinical use refers to the pharmaceutical product, which has since been withdrawn in the US. Open SVG
    1. Prakash A et al. Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency. BioDrugs. 1999;12:139-57.

  3. Compare two documented suppliers

    33 of 112 directory vendors list Sermorelin; 13 name their testing lab.

  4. Verify the lot before use

    1. Match the CAS number on the certificate to 86168-78-7.
    2. A 29-residue peptide should show a mass-spec identity near 3357.9 g/mol; HPLC purity alone doesn't confirm identity.
    3. 33 of the 112 vendors in our directory list Sermorelin; 13 of those name the lab that tests it.

FAQ

What is Sermorelin?

GHRH(1-29)-NH2, the shortest fully active fragment of growth hormone–releasing hormone. Sermorelin was used clinically to test and treat growth hormone deficiency in children before recombinant GH became standard.

What are Sermorelin's CAS number and molecular weight?

CAS 86168-78-7, formula C149H246N44O42S, 3357.9 g/mol, per PubChem CID 16132413.

Where can US labs buy Sermorelin?

Purgo Labs stocks it as “Sermorelin”; code usapeptidevendors takes 25% off at checkout. This page also lists the best-documented second vendor from our 112-vendor directory.

Is research-grade Sermorelin for human use?

No. Vendor material is sold for Research Use Only, not for human or veterinary use.