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Tissue research peptides

BPC-157

BPC-157 is one of the most searched research peptides in US vendor catalogs. UPV pages focus on lot documentation habits, not medical claims.

Updated 2026-11-08Body Protection Compound-157
Original illustration for BPC-157 research notes: abstract molecular artwork in orange and teal

Original illustration by USA Peptide Vendors. Artistic, not a structural model.

Chemistry facts

Amino acid sequence · 15 residues
  1. G1
  2. E2
  3. P3
  4. P4
  5. P5
  6. G6
  7. K7
  8. P8
  9. A9
  10. D10
  11. D11
  12. A12
  13. G13
  14. L14
  15. V15
CAS number
137525-51-0
Molecular formula
C62H98N16O22
Molecular weight
1419.5 g/mol
PubChem CID
9941957

Verified 2026-11-09 against PubChem CID 9941957. Values we could not verify are left out.

How BPC-157 is thought to work

Evidence level: Preclinical: cell culture and animal models. See every diagram in the mechanism map library.

BPC-157 mechanism diagramProposed VEGFR2–Akt–eNOS signaling in endothelial and tendon models. Targets: VEGFR2. Signaling reported: Akt → eNOS. Effects reported in models: Endothelial tube formation, Angiogenesis.BPC-157 mechanism mapProposed VEGFR2–Akt–eNOS signaling in endothelial and tendon modelsBPC-15715-residue peptideVEGFR2up-regulation and internalization [1]Akt[1]eNOS[1]Endothelial tube formationcell culture [1]AngiogenesisCAM assay, rat hind limb [1]Evidence: Preclinical: cell culture and animal models. Numbers in brackets refer to thecited sources.usapeptidevendors.com · Research Use OnlyPROPOSED TARGET (NO RECEPTOR CONFIRMED)SIGNALING REPORTEDEFFECTS REPORTED IN MODELS
No specific BPC-157 receptor has been identified. Separate tendon-fibroblast studies report FAK–paxillin activation [2] and higher growth hormone receptor expression [3]; they are not drawn as part of the VEGFR2 pathway. Open SVG
  1. Hsieh MJ et al. Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. J Mol Med. 2017;95:323–333.
  2. Chang CH et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol. 2011;110:774–780.
  3. Chang CH et al. Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Molecules. 2014;19:19066–19077.

Research context

Public literature discusses gastric-derived peptide fragments in preclinical models. USA Peptide Vendors does not interpret clinical outcomes; we map which vendors publish assay paperwork for labeled BPC-157 SKUs.

Buyer notes

  • Prefer lots with both purity % and measured content (mg) on the certificate
  • Confirm vial label lot string matches the PDF
  • Ask whether sterility/endotoxin panels exist if your protocol requires them

FAQ

What should a BPC-157 COA include?

At minimum: analyte identity, lot/batch ID, purity method (often HPLC), date, and lab name. Content assays (measured mg vs labeled mg) are a strong transparency signal.

Is BPC-157 approved for human use?

No. Materials discussed here are Research Use Only and not for human consumption.

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