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Original illustration for Ipamorelin research notes: abstract molecular artwork in orange and teal
Original illustration by USA Peptide Vendors; artistic, not a structural model.

Growth & signaling research peptides

Ipamorelin research guide in four steps

Synthetic pentapeptide agonist at the growth hormone secretagogue (ghrelin) receptor. Ipamorelin was introduced in 1998 as the first selective GH secretagogue: in animal studies it released growth hormone without raising ACTH or cortisol.

GrowthCAS 170851-70-4Ipamorlin (Purgo spelling)Updated 2026-11-09

  1. Confirm what Ipamorelin is

    Aib-His-D-2-Nal-D-Phe-Lys-NH2. Three of the five residues are non-standard, so the one-letter chain is not shown.

    CAS number
    170851-70-4
    Molecular formula
    C38H49N9O5
    Molecular weight
    711.9 g/mol
    PubChem CID
    9831659

    Verified 2026-11-09 against PubChem CID 9831659. Values we couldn't verify are left out.

  2. Know the proposed mechanism

    Ipamorelin was introduced in 1998 as the first selective GH secretagogue: in animal studies it released growth hormone without raising ACTH or cortisol.

    Mechanism map

    Evidence level: Preclinical: rat and swine studies. All mechanism maps

    Ipamorelin mechanism diagramSelective growth hormone release through the GH secretagogue receptor. Targets: GH secretagogue receptor. Site of action: Pituitary somatotrophs. Effects reported: GH release ↑, No ACTH or cortisol rise.Ipamorelin mechanism mapSelective growth hormone release through the GH secretagogue receptorIpamorelinpentapeptide secretagogueGH secretagogue receptorghrelin receptor [1]Pituitary somatotrophs[1]GH release ↑[1]No ACTH or cortisol riseat GH-releasing doses [1]Evidence: Preclinical: rat and swine studies. Numbers in brackets refer to the citedsources.usapeptidevendors.com · Research Use OnlyRECEPTORSITE OF ACTIONEFFECTS REPORTED
    Selectivity was shown in animals; human data are limited. Open SVG
    1. Raun K et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139:552-61.

  3. Compare two documented suppliers

    39 of 112 directory vendors list Ipamorelin; 18 name their testing lab.

  4. Verify the lot before use

    1. Purgo sells it as “Ipamorlin”. Make sure the COA names the analyte, not just the store label.
    2. Match the CAS number on the certificate to 170851-70-4.
    3. 39 of the 112 vendors in our directory list Ipamorelin; 18 of those name the lab that tests it.

FAQ

What is Ipamorelin?

Synthetic pentapeptide agonist at the growth hormone secretagogue (ghrelin) receptor. Ipamorelin was introduced in 1998 as the first selective GH secretagogue: in animal studies it released growth hormone without raising ACTH or cortisol.

What are Ipamorelin's CAS number and molecular weight?

CAS 170851-70-4, formula C38H49N9O5, 711.9 g/mol, per PubChem CID 9831659.

Where can US labs buy Ipamorelin?

Purgo Labs stocks it as “Ipamorlin”; code usapeptidevendors takes 25% off at checkout. This page also lists the best-documented second vendor from our 112-vendor directory.

Is research-grade Ipamorelin for human use?

No. Vendor material is sold for Research Use Only, not for human or veterinary use.