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Spec sheet · Metabolic & GLP

Tirzepatide: specs, mechanism and price check

Acylated 39-residue dual agonist at the GIP and GLP-1 receptors. Tirzepatide is weighted toward GIP receptor activity with weaker GLP-1 receptor agonism.

Metabolic & GLPCAS 2023788-19-239 residuesGLP-2 T (Purgo label)LY3298176Updated 2026-11-09
Original illustration for Tirzepatide research notes: abstract molecular artwork in orange and teal
Original illustration by USA Peptide Vendors; artistic, not a structural model.

Specifications

Amino acid sequence · 39 residues
  1. Y1
  2. X2
  3. E3
  4. G4
  5. T5
  6. F6
  7. T7
  8. S8
  9. D9
  10. Y10
  11. S11
  12. I12
  13. X13
  14. L14
  15. D15
  16. K16
  17. I17
  18. A18
  19. Q19
  20. K20
  21. A21
  22. F22
  23. V23
  24. Q24
  25. W25
  26. L26
  27. I27
  28. A28
  29. G29
  30. G30
  31. P31
  32. S32
  33. S33
  34. G34
  35. A35
  36. P36
  37. P37
  38. P38
  39. S39

Sequence as listed by KEGG. X is Aib; the lysine at position 20 carries a C20 fatty-diacid side chain.

PropertyValueSource
CAS number2023788-19-2KEGG DRUG D11360
Molecular formulaC225H348N48O68KEGG DRUG D11360
Molecular weight4813.45 g/molKEGG DRUG D11360
PubChem CID166567236KEGG DRUG D11360
Length39 residuesKEGG DRUG D11360

Verified 2026-11-09 against KEGG DRUG D11360 and PubChem CID 166567236. Values we couldn't verify are left out.

Price check: #1 vs #2

Purgo Labs vs the runner-up, from each vendor's own site
#1 Purgo Labs#2 Prime Peptides
Listed itemGLP-2 T 10mgTirzepatide 60mg
List price$49.99$240.00
With code$37.49 (25% off)No code
Proof Score100/10080/100
Testing labs namedILS Laboratories, Freedom Diagnostics +3Janoshik Analytical, Freedom Diagnostics +2
LinkGet 25% off by using code usapeptidevendorsPrime Peptides ↗

Receptor pharmacology

Evidence level: Clinical: discovery paper and phase 3 trial. All mechanism maps

Tirzepatide mechanism diagramDual agonist at the GIP and GLP-1 receptors, weighted toward GIP. Targets: GIPR, GLP-1R. Shared signaling: cAMP ↑. Effects reported: Glucose-dependent insulin secretion, Weight reduction.Tirzepatide mechanism mapDual agonist at the GIP and GLP-1 receptors, weighted toward GIPTirzepatideLY3298176, acylated peptideGIPRGIP receptor [1]GLP-1RGLP-1 receptor [1]cAMP ↑[1]Glucose-dependent insulinsecretion[1]Weight reductionSURMOUNT-1 trial [2]Evidence: Clinical: discovery paper and phase 3 trial. Numbers in brackets refer to thecited sources.usapeptidevendors.com · Research Use OnlyRECEPTORS (AGONIST AT BOTH)SHARED SIGNALINGEFFECTS REPORTED
Trial results apply to the pharmaceutical product, not to research-catalog vials. Open SVG
  1. Coskun T et al. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept. Mol Metab. 2018;18:3-14.
  2. Jastreboff AM et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022;387:205-216.

Research background

Tirzepatide is weighted toward GIP receptor activity with weaker GLP-1 receptor agonism. Its weight data come from the SURMOUNT trials of the pharmaceutical product.

5 of 112 directory vendors list Tirzepatide; 2 name their testing lab.

COA checklist

  1. Purgo sells it as “GLP-2 T”. Make sure the COA names the analyte, not just the store label.
  2. Match the CAS number on the certificate to 2023788-19-2.
  3. A 39-residue peptide should show a mass-spec identity near 4813.45 g/mol; HPLC purity alone doesn't confirm identity.
  4. 5 of the 112 vendors in our directory list Tirzepatide; 2 of those name the lab that tests it.
  5. Purgo lists this as “GLP-2 T”, an “acylated 39-amino-acid dual-pathway receptor agonist”, and gives tirzepatide's CAS number in its product data. Confirm the analyte on the COA.

Tirzepatide questions

What is Tirzepatide?

Acylated 39-residue dual agonist at the GIP and GLP-1 receptors. Tirzepatide is weighted toward GIP receptor activity with weaker GLP-1 receptor agonism. Its weight data come from the SURMOUNT trials of the pharmaceutical product.

What are Tirzepatide's CAS number and molecular weight?

CAS 2023788-19-2, formula C225H348N48O68, 4813.45 g/mol, per KEGG DRUG D11360 and PubChem CID 166567236.

Where can US labs buy Tirzepatide?

Purgo Labs stocks it as “GLP-2 T”; code usapeptidevendors takes 25% off at checkout. This page also lists the best-documented second vendor from our 112-vendor directory.

Is research-grade Tirzepatide for human use?

No. Vendor material is sold for Research Use Only, not for human or veterinary use.