Code usapeptidevendors: 25% off everything at · Purgo Labs

Related brand · disclosed
USA Peptide VendorsIndependent vendor reviews
Purgo Labsusapeptidevendors

Try

Cognitive explainer

What the research says about Semax

Synthetic heptapeptide: ACTH(4-7) extended with Pro-Gly-Pro.

CognitiveCAS 80714-61-07 residuesUpdated 2026-11-09
Original illustration for Semax research notes: abstract molecular artwork in orange and teal
Original illustration by USA Peptide Vendors; artistic, not a structural model.

What has actually been studied?

Semax was developed in Russia; rat studies report increased BDNF and TrkB expression in the hippocampus.

How is Semax thought to work?

Evidence level: Preclinical: rat studies. All mechanism maps

Semax mechanism diagramIncreased BDNF and TrkB expression in rat hippocampus. Targets: Hippocampus. Reported changes: BDNF ↑ → TrkB ↑. Proposed effect: Basis for cognitive effects.Semax mechanism mapIncreased BDNF and TrkB expression in rat hippocampusSemaxACTH(4-7)-Pro-Gly-ProHippocampusrat [1]BDNF ↑[1]TrkB ↑[1]Basis for cognitive effectsproposed [1]Evidence: Preclinical: rat studies. Numbers in brackets refer to the cited sources.usapeptidevendors.com · Research Use OnlyTISSUE STUDIEDREPORTED CHANGESPROPOSED EFFECT
No dedicated Semax receptor is established. Open SVG
  1. Dolotov OV et al. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Res. 2006;1117:54-60.

What does the molecule look like?

Amino acid sequence · 7 residues
  1. M1
  2. E2
  3. H3
  4. F4
  5. P5
  6. G6
  7. P7
  • CAS number80714-61-0
  • Molecular formulaC37H51N9O10S
  • Molecular weight813.9 g/mol
  • PubChem CID9811102
  • Length7 residues

Verified 2026-11-09 against PubChem CID 9811102. Values we couldn't verify are left out.

Where do US labs buy Semax?

42 of 112 directory vendors list Semax; 19 name their testing lab.

What should the certificate show?

  • Match the CAS number on the certificate to 80714-61-0.
  • A 7-residue peptide should show a mass-spec identity near 813.9 g/mol; HPLC purity alone doesn't confirm identity.
  • 42 of the 112 vendors in our directory list Semax; 19 of those name the lab that tests it.

Other questions researchers ask

What is Semax?

Synthetic heptapeptide: ACTH(4-7) extended with Pro-Gly-Pro. Semax was developed in Russia; rat studies report increased BDNF and TrkB expression in the hippocampus.

What are Semax's CAS number and molecular weight?

CAS 80714-61-0, formula C37H51N9O10S, 813.9 g/mol, per PubChem CID 9811102.

Where can US labs buy Semax?

Purgo Labs stocks it as “Semax”; code usapeptidevendors takes 25% off at checkout. This page also lists the best-documented second vendor from our 112-vendor directory.

Is research-grade Semax for human use?

No. Vendor material is sold for Research Use Only, not for human or veterinary use.