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Cognitive explainer

Pinealon, explained for researchers

Synthetic tripeptide Glu-Asp-Arg from the Khavinson group's short-peptide research.

CognitiveCAS 175175-23-23 residuesEDR peptideGlu-Asp-ArgUpdated 2026-11-09
Original illustration for Pinealon research notes: abstract molecular artwork in orange and teal
Original illustration by USA Peptide Vendors; artistic, not a structural model.

What has actually been studied?

Proposed to act on gene expression in neurons; the evidence is limited and mostly from one research group. Purgo sells it only in two spray blends.

How is Pinealon thought to work?

Evidence level: Limited: hypothesis and model data from one group. All mechanism maps

Pinealon mechanism diagramProposed gene-expression effects of the EDR tripeptide. Targets: DNA and chromatin. Proposed: Gene expression changes. Proposed effect: Neuron protection in models.Pinealon mechanism mapProposed gene-expression effects of the EDR tripeptidePinealonGlu-Asp-ArgDNA and chromatinproposed binding [1]Gene expression changes[1]Neuron protection in modelsproposed [1]Evidence: Limited: hypothesis and model data from one group. Numbers in brackets refer tothe cited sources.usapeptidevendors.com · Research Use OnlyPROPOSED TARGETPROPOSEDPROPOSED EFFECT
These are proposals from a single research group, not established mechanisms. Open SVG
  1. Khavinson V et al. EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease. Molecules. 2020;26.

What does the molecule look like?

Amino acid sequence · 3 residues
  1. E1
  2. D2
  3. R3
  • CAS number175175-23-2
  • Molecular formulaC15H26N6O8
  • Molecular weight418.40 g/mol
  • PubChem CID10273502
  • Length3 residues

Verified 2026-11-09 against PubChem CID 10273502. Values we couldn't verify are left out.

Where do US labs buy Pinealon?

What should the certificate show?

  • Match the CAS number on the certificate to 175175-23-2.
  • A 3-residue peptide should show a mass-spec identity near 418.40 g/mol; HPLC purity alone doesn't confirm identity.

Other questions researchers ask

What is Pinealon?

Synthetic tripeptide Glu-Asp-Arg from the Khavinson group's short-peptide research. Proposed to act on gene expression in neurons; the evidence is limited and mostly from one research group. Purgo sells it only in two spray blends.

What are Pinealon's CAS number and molecular weight?

CAS 175175-23-2, formula C15H26N6O8, 418.40 g/mol, per PubChem CID 10273502.

Is research-grade Pinealon for human use?

No. Vendor material is sold for Research Use Only, not for human or veterinary use.