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Spray · Cofactors & Diluents

NAD+ Spray — how the spray compares

Ready-mixed NAD+ spray labeled 1500mg. NAD+ breaks down in solution faster than as dry powder, so check the batch date and storage guidance.

Cofactors & DiluentsCAS 53-84-9SprayUpdated 2026-11-09
Original illustration for NAD+ Spray research notes: abstract molecular artwork in orange and teal
Original illustration by USA Peptide Vendors; artistic, not a structural model.

Spray vs lyophilized vial

NAD+ SprayNAD+ vial
FormSprayLyophilized powder
What's in itReady-mixed NAD+ spray labeled 1500mg.NAD+ research vials are common staples. Look for content assays that show measured mass near labeled strength.
PrepReady to use; no reconstitutionReconstituted with bacteriostatic or sterile water
Published dataNone specific to this formatEstablished biochemistry (review)
Analyte CAS53-84-953-84-9

Full chemistry, sequence and sourcing for the vial: NAD+ →

About this format

NAD+ breaks down in solution faster than as dry powder, so check the batch date and storage guidance.

Format checks

  • The spray carries the same analyte as NAD+ vials; check that the COA covers this format's lot, not a vial lot.
  • 44 of the 112 vendors in our directory list NAD+; 20 of those name the lab that tests it.

Mechanism of NAD+

Evidence level: Established biochemistry (review). This diagram is for NAD+ itself; the spray hasn't been studied separately. All mechanism maps

NAD+ mechanism diagramRedox cofactor and substrate for NAD+-consuming enzymes. Targets: Redox cofactor, Sirtuins, PARPs. Recycling after consumption (salvage pathway): Nicotinamide → NAMPT → NMN → NAD+. Downstream processes: Energy metabolism, Protein deacylation, DNA-damage signaling.NAD+ mechanism mapRedox cofactor and substrate for NAD+-consuming enzymesNAD+dinucleotide cofactorRedox cofactorNAD+ ⇄ NADH [1]SirtuinsSIRT1–7 substrate [1]PARPsPARP1 and others [1]Energy metabolismglycolysis, TCA, OXPHOS[1]Protein deacylationsirtuins [1]DNA-damage signalingPARPs [1]Nicotinamide[1]NAMPT[1]NMN → NAD+[1]Evidence: Established biochemistry (review). Numbers in brackets refer to the citedsources.usapeptidevendors.com · Research Use OnlyROLES IN THE CELLDOWNSTREAM PROCESSESRECYCLING AFTER CONSUMPTION (SALVAGE PATHWAY)
This diagram shows intracellular NAD+ biology. How well supplied NAD+ is taken up by cells is still debated. Open SVG
  1. Covarrubias AJ et al. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021;22:119–141.

FAQ

What is NAD+ Spray?

Ready-mixed NAD+ spray labeled 1500mg. NAD+ breaks down in solution faster than as dry powder, so check the batch date and storage guidance.

How is NAD+ Spray different from a NAD+ vial?

Ready-mixed NAD+ spray labeled 1500mg. A lyophilized vial is reconstituted by the lab; the spray is pre-made, so stability and per-unit content depend on the vendor's formulation.

Where can US labs buy NAD+ Spray?

Purgo Labs stocks it as “NAD+ Spray”; code usapeptidevendors takes 25% off at checkout. This page also lists the best-documented second vendor from our 112-vendor directory.

Is research-grade NAD+ Spray for human use?

No. Vendor material is sold for Research Use Only, not for human or veterinary use.