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Cofactor research materials

NAD+

NAD+ research vials are common staples. Look for content assays that show measured mass near labeled strength.

Updated 2026-11-05Nicotinamide adenine dinucleotide
Original illustration for NAD+ research notes: abstract molecular artwork in orange and teal

Original illustration by USA Peptide Vendors. Artistic, not a structural model.

Chemistry facts

CAS number
53-84-9
Molecular formula
C21H27N7O14P2
Molecular weight
663.4 g/mol
PubChem CID
5892

NAD+ is a dinucleotide cofactor, not a peptide, so it has no amino acid sequence.

Verified 2026-11-09 against PubChem CID 5892. Values we could not verify are left out.

How NAD+ is thought to work

Evidence level: Established biochemistry (review). See every diagram in the mechanism map library.

NAD+ mechanism diagramRedox cofactor and substrate for NAD+-consuming enzymes. Targets: Redox cofactor, Sirtuins, PARPs. Recycling after consumption (salvage pathway): Nicotinamide → NAMPT → NMN → NAD+. Downstream processes: Energy metabolism, Protein deacylation, DNA-damage signaling.NAD+ mechanism mapRedox cofactor and substrate for NAD+-consuming enzymesNAD+dinucleotide cofactorRedox cofactorNAD+ ⇄ NADH [1]SirtuinsSIRT1–7 substrate [1]PARPsPARP1 and others [1]Energy metabolismglycolysis, TCA, OXPHOS[1]Protein deacylationsirtuins [1]DNA-damage signalingPARPs [1]Nicotinamide[1]NAMPT[1]NMN → NAD+[1]Evidence: Established biochemistry (review). Numbers in brackets refer to the citedsources.usapeptidevendors.com · Research Use OnlyROLES IN THE CELLDOWNSTREAM PROCESSESRECYCLING AFTER CONSUMPTION (SALVAGE PATHWAY)
This diagram shows intracellular NAD+ biology. How well supplied NAD+ is taken up by cells is still debated. Open SVG
  1. Covarrubias AJ et al. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021;22:119–141.

Research context

UPV highlights vendors that publish lab-hosted certificates for NAD+ lots rather than undated marketing PDFs.

Buyer notes

  • Content assay (measured mg) is especially useful for NAD+ lots
  • Check storage guidance on the vendor FAQ for lab handling

FAQ

What makes a strong NAD+ vendor page?

Lot ID, dated assay, measured content, and unambiguous RUO labeling.

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