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Recovery research peptides

KPV: lab dossier and sourcing

C-terminal tripeptide of α-MSH (Lys-Pro-Val). In mouse colitis models, KPV taken up through the PepT1 transporter reduced intestinal inflammation.

RecoveryCAS 67727-97-33 residuesLys-Pro-Valα-MSH (11-13)Updated 2026-11-09
Original illustration for KPV research notes: abstract molecular artwork in orange and teal
Original illustration by USA Peptide Vendors; artistic, not a structural model.

At a glance

Amino acid sequence · 3 residues
  1. K1
  2. P2
  3. V3
CAS number
67727-97-3
Molecular formula
C16H30N4O4
Molecular weight
342.43 g/mol
PubChem CID
125672
Length
3 residues

Purgo's product data lists a different CAS number and weight; the values above are PubChem's.

Verified 2026-11-09 against PubChem CID 125672. Values we couldn't verify are left out.

What the literature covers

In mouse colitis models, KPV taken up through the PepT1 transporter reduced intestinal inflammation.

39 of 112 directory vendors list KPV; 18 name their testing lab.

Proposed KPV signaling

Evidence level: Preclinical: cell culture and mouse colitis. All mechanism maps

KPV mechanism diagramPepT1-mediated uptake and reduced inflammatory signaling in gut models. Targets: PepT1 transporter. Signaling reported: NF-κB and MAPK ↓. Effect reported: Intestinal inflammation ↓.KPV mechanism mapPepT1-mediated uptake and reduced inflammatory signaling in gut modelsKPVLys-Pro-ValPepT1 transporterintestinal epithelium [1]NF-κB and MAPK ↓[1]Intestinal inflammation ↓mouse colitis [1]Evidence: Preclinical: cell culture and mouse colitis. Numbers in brackets refer to thecited sources.usapeptidevendors.com · Research Use OnlyUPTAKE ROUTESIGNALING REPORTEDEFFECT REPORTED
Animal and cell data only. Open SVG
  1. Dalmasso G et al. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology. 2008;134:166-78.

Before you order

  • Match the CAS number on the certificate to 67727-97-3.
  • A 3-residue peptide should show a mass-spec identity near 342.43 g/mol; HPLC purity alone doesn't confirm identity.
  • 39 of the 112 vendors in our directory list KPV; 18 of those name the lab that tests it.

FAQ

What is KPV?

C-terminal tripeptide of α-MSH (Lys-Pro-Val). In mouse colitis models, KPV taken up through the PepT1 transporter reduced intestinal inflammation.

What are KPV's CAS number and molecular weight?

CAS 67727-97-3, formula C16H30N4O4, 342.43 g/mol, per PubChem CID 125672. Purgo's product data lists a different CAS number and weight; the values above are PubChem's.

Where can US labs buy KPV?

Purgo Labs stocks it as “KPV”; code usapeptidevendors takes 25% off at checkout. This page also lists the best-documented second vendor from our 112-vendor directory.

Is research-grade KPV for human use?

No. Vendor material is sold for Research Use Only, not for human or veterinary use.