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Spray · Skin & Melanocortin

GHK-Cu Spray — how the spray compares

Ready-mixed 50mg GHK-Cu spray; no reconstitution needed. Same analyte as the GHK-Cu vial, pre-dissolved.

Skin & MelanocortinCAS 89030-95-53 residuesSprayUpdated 2026-11-09
Original illustration for GHK-Cu Spray research notes: abstract molecular artwork in orange and teal
Original illustration by USA Peptide Vendors; artistic, not a structural model.

Spray vs lyophilized vial

GHK-Cu SprayGHK-Cu vial
FormSprayLyophilized powder
What's in itReady-mixed 50mg GHK-Cu spray; no reconstitution needed.Copper(II) complex of the tripeptide Gly-His-Lys. GHK-Cu stimulated collagen synthesis in fibroblast culture in 1988 and has since been studied in wound and skin models.
PrepReady to use; no reconstitutionReconstituted with bacteriostatic or sterile water
Published dataNone specific to this formatPreclinical: cell culture and wound models
Analyte CAS89030-95-589030-95-5

Full chemistry, sequence and sourcing for the vial: GHK-Cu →

About this format

Same analyte as the GHK-Cu vial, pre-dissolved. Ask for the solution's COA, not just the raw peptide's.

Format checks

  • The spray carries the same analyte as GHK-Cu vials; check that the COA covers this format's lot, not a vial lot.
  • 43 of the 112 vendors in our directory list GHK-Cu; 20 of those name the lab that tests it.

Mechanism of GHK-Cu

Evidence level: Preclinical: cell culture and wound models. This diagram is for GHK-Cu itself; the spray hasn't been studied separately. All mechanism maps

GHK-Cu mechanism diagramCopper delivery and fibroblast gene expression in skin and wound models. Targets: Cu(II) delivery to cells. Reported response: Fibroblast gene expression changes. Effects reported: Collagen synthesis ↑, Wound matrix remodeling.GHK-Cu mechanism mapCopper delivery and fibroblast gene expression in skin and wound modelsGHK-Cucopper tripeptideCu(II) delivery to cells[2]Fibroblast gene expression changes[2]Collagen synthesis ↑fibroblast culture [1]Wound matrix remodelingrat wounds [3]Evidence: Preclinical: cell culture and wound models. Numbers in brackets refer to thecited sources.usapeptidevendors.com · Research Use OnlyPROPOSED ACTIONREPORTED RESPONSEEFFECTS REPORTED
Gene-expression data are largely from database analyses; the copper-delivery model is proposed. Open SVG
  1. Maquart FX et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Lett. 1988;238:343-6.
  2. Pickart L et al. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018;19.
  3. Siméon A et al. Expression of glycosaminoglycans and small proteoglycans in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu(2+). J Invest Dermatol. 2000;115:962-8.

FAQ

What is GHK-Cu Spray?

Ready-mixed 50mg GHK-Cu spray; no reconstitution needed. Same analyte as the GHK-Cu vial, pre-dissolved. Ask for the solution's COA, not just the raw peptide's.

How is GHK-Cu Spray different from a GHK-Cu vial?

Ready-mixed 50mg GHK-Cu spray; no reconstitution needed. A lyophilized vial is reconstituted by the lab; the spray is pre-made, so stability and per-unit content depend on the vendor's formulation.

Where can US labs buy GHK-Cu Spray?

Purgo Labs stocks it as “GHK-CU Spray”; code usapeptidevendors takes 25% off at checkout. This page also lists the best-documented second vendor from our 112-vendor directory.

Is research-grade GHK-Cu Spray for human use?

No. Vendor material is sold for Research Use Only, not for human or veterinary use.