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Multi-peptide blend · 2 components

GLP-4 Meta, component by component

12mg vial with 10mg GLP-3 R and 2mg PEG-MGF.

Multi-Peptide BlendsMetatrutideUpdated 2026-11-09

Per-vial contents

Combination untested. Despite the “GLP-4” name, Purgo describes it as GLP-3 R plus PEG-MGF; it is not a fourth incretin agonist.
Original illustration for GLP-4 Meta (GLP-3 R + PEG-MGF) research notes: abstract molecular artwork in orange and teal
Original illustration by USA Peptide Vendors; artistic, not a structural model.

What each component does on its own

Evidence level: Components only: no study has tested this combination. All mechanism maps

GLP-4 Meta mechanism diagramEach component's own reported mechanism, side by side. Targets: Retatrutide: GIPR, PEG-MGF: Myoblasts. : . Effect reported for that component alone: Calorie intake ↓, Differentiation delayed.GLP-4 Meta mechanism mapEach component's own reported mechanism, side by sideGLP-4 Meta2-component blendRetatrutide: GIPRGIP receptor [1]PEG-MGF: Myoblasts[2]Calorie intake ↓GIPR + GLP-1R, mice [1]Differentiation delayed[2]Evidence: Components only: no study has tested this combination. Numbers in brackets referto the cited sources.usapeptidevendors.com · Research Use OnlyCOMPONENT → REPORTED TARGETEFFECT REPORTED FOR THAT COMPONENT ALONE
Each row comes from studies of that peptide on its own. Whether the blend behaves like the sum of its parts has not been studied. Open SVG
  1. Coskun T et al. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss. Cell Metab. 2022;34:1234–1247.
  2. Yang SY et al. Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation. FEBS Lett. 2002;522:156-60.

Blend-specific checks

  • Ask for net content per component: Retatrutide (10mg), PEG-MGF (2mg). A single purity figure for the vial doesn't cover each peptide.
  • Sold as “GLP-4 Meta” under the handle “metatrutide”. Neither is a recognised compound name; the stated contents are 10mg GLP-3 + 2mg PEG-MGF.

FAQ

What is GLP-4 Meta (GLP-3 R + PEG-MGF)?

12mg vial with 10mg GLP-3 R and 2mg PEG-MGF. Despite the “GLP-4” name, Purgo describes it as GLP-3 R plus PEG-MGF; it is not a fourth incretin agonist.

What's in GLP-4 Meta (GLP-3 R + PEG-MGF)?

Retatrutide 10mg, PEG-MGF 2mg. No published study has tested this exact combination; each component's evidence is separate.

Where can US labs buy GLP-4 Meta (GLP-3 R + PEG-MGF)?

Purgo Labs stocks it as “GLP-4 Meta”; code usapeptidevendors takes 25% off at checkout. This page also lists the best-documented second vendor from our 112-vendor directory.

Is research-grade GLP-4 Meta (GLP-3 R + PEG-MGF) for human use?

No. Vendor material is sold for Research Use Only, not for human or veterinary use.